INTERPRETATION
How to interpret the values (in the Ketonix App).
Here is a description of how values of a healthy normal persion could be iinterpreted.
Ketosis isn't a steady value you have throughout the day, it can vary a lot depending on what you are doing. Whenever your levels of insulin rise ketosis goes down. Commonly ketosis decrease after meals (body stores excess energy), during and up to an hour after exercise (body produces glucose). Ketosis may even for some decrease during first days of fasting when liver releases glucose in response to glucagon.
Values in the black range means your liver isn't producing a lot of ketones at the moment.
If you get values in the green range, you are in nutritional ketosis. This means you eat low carb and use fat as fuel (for some this nutritional ketosis also causes weight loss). This range indicates a maintenance ketogenic lifestyle.
Values in the yellow range commonly are associated with caloric deficit combined with a ketogenic diet. The caloric deficit could be caused by exercise or intermittent fasting (or a combination thereof). Having values in this range (or above) is likely causing weight-loss. Getting into this range normally requires you to lower your glycogen stores. Depending on your tool to do this (exercise or fasting or both) and your current glycogen storage, it could take more or less time.
The range for breath ketones are 0 up to 1000 PPM in some cases. The Ketonix range is tested from 0 up to 200 PPM.
There is no way to correlate a blood ketones with breath ketones. Breath ketones are formed when the liver produce ketones. Blood ketones are formed when the energy need of the cell's decease (e.g ketosis decrease). Breath ketones are not accumulated like the blood ketones are. The blood ketones can exist in blood until needed again.
Breath ketones indicate the current level of ketosis.
Blood ketones indicate that your cells saved excess ketone energy into a storage form, and these buffers haven't been used yet. It is only of value for people having type 1 diabetes to check if the blood ketones are accumulating, for us others ... the blood ketones can be anything. For example: A blood ketone value of 3.5 mmol equals approximately 15 calories, it is very easy for your cells to use those blood ketones at any time. Even a short period of activity could trigger your cells to use them up.
How to translate PPM into mmol/L
PPM is a unit describing concentrations in gases (normally).
It means how many molecules out of a million molecules something is.
In this context it is how many molecules of acetone there is per million molecules in your breath.
Mmol/L is normally used in liquids, in this context people usually mean "blood ketones".
Now, ketones in breath is Acetone, blood ketones is the molecule Beta-Hydroxybutyrate (a stable molecule with an encapsulated AcetoAcetate.
So not the same medium or molecules.
Adding more to the sauce is that they are not created at the same time.
Breath acetone is formed when liver produce AcetoAcetate from free fatty acids, and reflects ketosis.
Blood ketones indicates a decreasing need for ketones or an issue to use them. Blood ketone tests where developed for those who have diabetes type 1. When their glucose levels are high, their cells can't metabolize the Beta-Hydroxybutyrate molecules, and the result is a blood with both high glcucose and Beta-hydroxybutyrate.
Analyze values
Setting a baseline
A baseline is a series of measures done at specific times per day during a week.
It could be measuring before breakfast at 06:00, before lunch at 11:30, before exercise at 17:30 and before bedtime at 22:00, every day for a week.
Body is using hormones at different times and situations. The hormones affect how energy is released, used and created and therefore ketosis is also affected.
Take a typical week and do these measures.
Evaluate lifestyle changes
When introducing ifestyle changes like diet, sleep, exercise etc. You should use the same scheme for measures like in the baseline. If a lifestyle change, increase the levels of breath ketones it means your body use more of the extra fat for energy.
Before your cells adopt using fat, they are used to using glucose. Your glycogen levels will decrease fast, and signals to release energy will be sent (glucagon).
When glucagon is signalling that energy is needed, glucose levels will rise until glycogen levels are low. This means ketosis will decrease for a short period in the transition to higher ketosis.
Any lifestyle change that lowers the glycogen stores (anaerobic exercise, fasting ....etc) will increase ketosis when glycogen gets low.
Just fasting alone, might take a few days before glycogen becomes low enough to rise ketosis. Intermittent fasting takes a little bit longer. Key is to not cheat,and fill the glycogen storages up.
Weight lifting is great as it maximize the usage of glucose in your cells. And so is HIIT exercises. A note on HIIT, make sure you let your cells replenish their glucose between the high-intensity periods. To short rest between the maximum outtake, will not get maximum effect .. however it will make you and your muscles very tired!
Evaluate exercise
When exercising, the body gets stressed and tries to organize all available energy to make the required effort. This means glycogen is converted into glucose.. and ketosis decrease.
Burning fat during exercise ... can be done, but needs to exhaust the glycogen stores first.
Exercise in the "fat burning zone" have two different outcomes depending on if your cells are fat-adapted or not.
If your cells aren't "fat-adapted" they prefer glucose, and glucose is used even in the "fat-burning" intensity. Stored glycogen wil be used and ketosis will elevate.
If your cells are "fat-adapted", they use the intramuscular fat direct, not releasing extra fat and make it into ketones in the liver. Mainly the ketones produced are aimed for brain and heart.
So, if evaluating different exercises, do the exercise in the afternoon/evening .. don't refill with carbs before or after the exercise. Use plain water and salt instead.
Beware that, to much salt can make your body react ....
Then measure earliest two hours after exercise, the increased glucose would then be taken care of, and the ketosis starts. Then measure the morning after before any food/exercise ... etc.
If exercise was targeting your glycogen, ketosis should have rised (compare to baseline).
The ketosis from a good workout, could be elevated as long as a day after.
Evaluate fasting
When starting out a fasting period, your body will release a hormone called glucagon. It signals "release energy! We are not getting any in!".
So if your glycogen storage is full, it might take some time before ketosis kicks in.
Ketonix is a great tool to see when this happens.
The time before ketosis elevates, highly depends on your levels of glycogen in the liver and your metabolic rate and history of dieting.
For me, it takes about three days before liver becomes low enough to signal "ketosis!!!".
Example:
Fasting for me is: water and some salt. After three days morning ketosis elevates quick.
Evaluate high carbohydrate diet
f you follow a high carb diet and want to track your ketones, we suggest you track them in the morning before breakfast. High Carb meals could for some produce methane from bacteria breaking down carbohydrates and for others cause a reactive / postprandial hypoglycemia. This is when your pancreas produces an insulin response that is too strong and your glucose and insulin levels become very low. To protect your brain, ketogenesis will supply your brain with energy, hence the ketone response.
Testing in the morning before breakfast would have the least effect on your breath ketones. A large glas of cold water before testing is adviced.
Why Choose Us?
The founder of Ketonix have epilepsy and needed a tool to manage his ketosis. We who work here use a low-carb diet for health and stay focused, the Ketonix device enables us to tweak our lifestyle and optimize our performance.
Our MISSION
Our mission is to provide a simple, cost effective and painless method to know if your body is in ketosis and the strength of it. With the insight of your level of ketosis you could adjust your actions to increase/maintain your ketosis.
Ketosis is when your insulin levels are low and your liver starts to metabolize fat into ketone energy. When ketones fuel our brain we sense a high mental clarity and energy boost. Without the ability to get into ketosis when glucose and glycogen is low the human man kind would not exist.
Ketosis is not the the same condition as Ketoacidosis. Ketoacidosis is is a complication of type 1 diabetes mellitus. It's a life-threatening condition resulting from dangerously high levels of ketones and blood sugar.
Ketonix® analyze your breath for the ketone named Acetone. Acetone is spontaneously released from the liver when ketone energy is formed.
The more fat that is mobilized into energy, the more Acetone in your breath.
Don't mixup breath ketones with blood ketones. Blood ketones are formed from excess ketone energy and could be converted back into energy at any time. In some situations one could say that they correlate, higher breath ketone level and you might find more blood ketones. Then add that your body could have issues both creating them and use them for energy, these factors makes it harder to interpret blood ketones. This is one of the reasons Ketonix® was invented, to indicate the strength of ketosis.